One of the most important needs of the pharmaceutical industry is to design or develop a drug that would cure or considerably cut down nicotine craving. In other words, they need to develop a drug that would cure the problem of smoking. The FDA says smoking is the most preventable cause of death in America. Not only is it the cause of a long list of cancers, but it is also the cause of heart and lung diseases. The agency says it is committed to helping smokers find effective ways of giving up. According to an estimate, there are more than 48 million smokers in America and out of these 48 million; 45 million are ready to do anything to quit this habit of smoking. But problem is not this. Smokers hardly forget the pleasure, the tobacco provides them settling into brain receptors and triggering natural pleasure and feel-good endorphins. Here rises the main problem. Many people start this no-smoking practice but can’t continue it for too long. The problem with modern tobacco is that the other chemical, which includes toxins and carcinogens that impose huge health, risks on the smokers. Just like there are many brands of cigarettes there are many treatments to quit smoking. Nicotine replacement therapy is one of the most popular paths for many smoking quitters to take. One can choose from nicotine patches, gums and nasal sprays. Beyond that you can start look at prescription treatments like chantix and zyban - the two most popular pills to help you quit. Out of these two drugs chantix also known as varenicline is proving itself to be a milestone in the industry of anti-smoking drugs. The FDA has approved chantix (varenicline tartrate) tablets for the treatment of smoking cessation - to help smokers give up smoking. Chantix, which works on specific parts of the brain, helps people give up smoking in two ways. There are reasons why chantix has gained more popularity than zyban. According to information of JAMA (Journal of the American Medical Association) chantix (varenicline) is four times as effective in helping a smoker give up cigarettes successfully. According to that report only, chantix is twice as effective as zyban (bupropion). Dr. Steven Galson, director of FDA's center for drug evaluation and research, says nicotine addiction makes it very hard for smokers to give up. According to him chantix is a proven and effective treatment for smokers who want to quit smoking. The FDA approved this anti-smoking drug chantix in May 2006.

Basically smokers often feel a sense of coolness and respite when they smoke or light up a cigarette. Chantix doesn’t let them feel these sensations. Chantix also lessens the withdrawal indications, which are very rigorous for some quite often. Chantix works in a different way from nicotine-replacement therapies. In nicotine-replacement therapies, a small dose of nicotine is given with the motive to provide the smoker with this drug while the patient rise above the huge psychological and physical troubles that come while giving up smoking. The other medicine zyban weakens the reuptake of addiction-linked brain chemicals through neurons i.e. dopamanine and norepinephrine. Chantix makes the patient produce more dopamine, which helps in lowering the cravings - at the same time brain cell receptors that help perpetuate addiction are blocked.

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