On the other hand several clinical trials have failed to show that taking only one or two so-called "strong" antioxidants like vitamins C, E or Co-enzyme Q10 provides any benefit at all. In fact vitamin C in high doses (1000 mg per day) can be harmful as it slows post event recovery and aggravates muscle inflammation commonly associated with vigorous exercise.

Plants provide an extensive range of valuable antioxidants and natural anti-inflammatory compounds. Spices are the richest food source of these compounds followed by fruit, vegetables, nuts and beverages such as tea and coffee. Scientists have discovered that many plant-based antioxidants are vitally important in the prevention of diseases such as heart disease, cancer and Alzheimer's disease – just some of the illnesses that are associated with free radical damage. As these plant compounds are powerful, effective free radical scavengers it is not surprising that they provide benefits to athletes who are frequently exposed to free radical-induced oxidative stress.

Antioxidant variety is more important than the strength of individual antioxidants. While it is important for everyone to ensure that they have an adequate intake of antioxidants, it is unwise to take excessive amounts of only one or two antioxidants like vitamin C or E as they may do more harm than good. To ensure optimum protection against free radical damage, endurance athletes need to eat sufficient quantities of fruit, vegetables and spices and take a supplement rich in an array of different plant-based antioxidants. Spice supplements provide the most comprehensive antioxidant protection for endurance athletes.

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